DILIsym® is a “middle-out”, multi scale computational model of drug-induced liver injury (DILI). The software is designed to be used during drug development to provide an enhanced understanding of the DILI hazard posed by individual molecules and to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.
The DILI-sim Initiative is a consortium of life science companies led by DILIsym Services, Inc. and charged with developing the DILIsym® software. The goals of the Initiative are to improve patient safety, reduce the need for animal testing, and reduce the costs and time necessary to develop new drugs.
The Initiative is led by Dr. Paul B. Watkins, Director of the University of North Carolina Institute for Drug Safety Sciences, located in the heart of Research Triangle Park, North Carolina.