Careers

The DILI-sim Initiative regularly seeks high quality people to join us and contribute to the development and use of the DILIsym® modeling software. We offer a unique mix of basic and applied research in the area of mathematical modeling. DILI-sim modeling team members join as employees of DILIsym Services Inc. As new team members are sought, positions will be posted here and linked to the DILIsym Services Careers website.

DILIsym Services Inc. offers competitive salaries, attractive benefits, a stimulating work environment, and coworkers with diverse backgrounds. As a matter of practice, DILIsym Services makes applications for general employment available only when a position is open and advertised. DILIsym Services Inc. is an Equal Employment Opportunity employer.

Current Openings

Modeling and Simulation Scientist at DILIsym Services Inc. Focused on Developing and Using Simulation Platforms for Drug Toxicity and Efficacy

Outstanding candidates are sought for a Scientist position at DILIsym Services Inc., a Simulations Plus Company (NASDAQ:SLP), located in Research Triangle Park, NC.  Various levels of experience will be considered for the possible roles of Scientist I, Scientist II, Senior Scientist or Principal Scientist.  The successful applicant will be part of an interdisciplinary team of engineers, biochemists, toxicologists, and physicians working on the development and application of the DILIsym® and/or NAFLDsym® software platforms, computational models focused on liver function in human patients, rodents, and dogs.  DILIsym focuses on drug-induced liver injury (DILI) while NAFLDsym focuses on non-alcoholic fatty liver disease (NAFLD).  Specifically, the successful candidate will be tasked with software development projects commissioned by the DILI-sim Initiative members (www.DILIsym.com) or arising from NAFLDsym use cases, as well as application projects that involve utilizing DILIsym and NAFLDsym to solve important problems related to drug efficacy and toxicity within the pharmaceutical industry.  The role will require a combination of technical and project management work, and will include components such as systems pharmacology modeling, software code development and maintenance in MATLAB®, report and manuscript preparation, presentations to DILI-sim members and sponsors of proprietary work, and training others on the use of DILIsym and NAFLDsym.

Qualifications and Experience

Ideal candidates will have a Ph.D. or equivalent degree in engineering, pharmaceutical sciences, or other life science areas with 5-20+ years of experience in the pharmaceutical or CRO space, or a M.S. or equivalent degree with 7-20+ years of experience.  They will be proficient in mathematics, have a general knowledge of biology, biochemistry, lipid biochemistry, immunology, and/or toxicology, and have experience with software such as MATLAB.  They will have experience in the areas of PK modeling, PKPD modeling, and systems pharmacology modeling.  They will also have experience with appropriate software platforms in each of these areas (e.g. MATLAB, GastroPlus™, C++ programming).  Finally, they will have an extensive knowledge of the drug development process and how to apply modeling and simulation to the process for maximum impact. 

Qualified candidates need to submit their resume as a PDF document to Bud Nelson at This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Postdoctoral Training Position in Modeling and Simulation of Drug-Induced Liver Injury or Fatty Liver Disease Therapies

Outstanding candidates are sought for postdoctoral positions at DILIsym Services Inc., a Simulations Plus company, in Research Triangle Park, NC. The successful applicants will be part of an interdisciplinary team of engineers, biochemists, toxicologists, and physicians working on the development and application of the DILIsym® software, a computational model of liver function in human patients, rodents, and dogs to improve understanding of drug-induced liver injury (DILI). Specifically, the successful candidates will be tasked with DILIsym software development projects commissioned by the DILI-sim Initiative members (www.DILIsym.com), as well as application projects that involve utilizing DILIsym to solve important problems related to drug-induced liver injury within the pharmaceutical industry. Candidates may also spend time on the development and use of NAFLDsym, a mathematical software representation of Non-alcoholic Fatty Liver Disease used for the evaluation of disease treatments. The initial appointment will be for one year, with the possibility of extension.

Qualifications and Experience

Ideal candidates will have a Ph.D. or equivalent degree in engineering, pharmaceutical sciences, or other life science areas with 0-3 years of postdoctoral study experience. They will be proficient in mathematics, have a general knowledge of biology, biochemistry, and toxicology, and have experience with software such as MATLAB. A background knowledge of liver biochemistry and physiology or metabolic diseases is desirable but not required. Experience and familiarity with computational modeling of biological systems is desirable but not essential.

Qualified candidates need to submit their resume to Bud Nelson, Director of Operations, at This email address is being protected from spambots. You need JavaScript enabled to view it..

Companies Supporting DILIsym® Software Development

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