Grant Generaux, M.S.

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Address

  • 6 Davis Drive
    P.O. Box 12137
  • Research Triangle Park, NC 27709-2137
  • USA

Scientist, DILIsym Services, Inc.
Developer, DILI-sim Initiative

Grant Generaux, M.S., is a scientist for DILIsym Services, Inc. and a software developer working on the DILI-sim Initiative modeling team. He joined the DILIsym® software modeling team in June 2015.

Grant worked in Drug Metabolism and Pharmacokinetics (DMPK) at GlaxoSmithKline (GSK) for 10 years, with the majority of that time focused on using mechanistic PBPK/PD to improve decision making during drug discovery and early development. He also focused on predicting metabolic- and transporter-based drug-drug interactions. While at GSK, he was one of the key individuals who drove the evaluation and adoption of SimCYP for pre-clinical drug-drug interaction prediction and analysis, and was the recipient of the GSK “Exceptional Science Award” on three separate occasions as a result of the impact that SimCYP, and PBPK use in general, had on decision-making within the pre-clinical and clinical pipeline.

Grant has been an invited speaker at the Land O’Lakes conference on Drug Metabolism and Applied Pharmacokinetics, as well as the HIV & Hepatitis Clinical Pharmacology Workshop. He obtained his bachelor of science in genetics from the University of Kansas in 2000 and his master of science in pharmacometrics from the University of Maryland at Baltimore in 2014.